Meclizine dihydrochloride | Tocris Bioscience 4245 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Meclizine dihydrochloride

catalog :

4245

quantity :

50 mg

price :

105 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Hong C, Chau K, Schapira A. Meclizine-induced enhanced glycolysis is neuroprotective in Parkinson disease cell models. Sci Rep. 2016;6:25344 pubmed publisher

product information

brand :

Tocris

master code :

4245

SKU :

4245/50

product name :

Meclizine dihydrochloride

description :

Human pregnane X receptor agonist; H1 antagonist

target :

Pregnane X Receptor Agonists

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

463.87

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Human pregnane X receptor (hPXR) agonist; stronger activator of hPXR than rat PXR. Increases hPXR target gene expression in human hepatocyte primary cultures. Also acts as a histamine H1 receptor antagonist. Confers neuroprotection in models of polyQ toxicity.

catalog number base :

4245

product keywords :

antihistamine histaminergic pregnane x receptors pxr hpxr agonists activators neuroprotective neuroprotectants meclozine Meclozine Histamine H1 Receptors Pregnane X Receptor 4245,

extended description :

Human pregnane X receptor agonist; H1 antagonist

chemical name text :

1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazine dihydrochloride

formula :

C 25 H 27 ClN 2 .2HCl

formula text :

C25H27ClN2.2HCl

cas num :

1104-22-9

2020 USD :

101

2021 USD :

105 USD

alt names :

Meclozine

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage