SCH 529074 | Tocris Bioscience 4240 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SCH 529074

catalog :

4240

quantity :

10 mg (also 50 mg)

price :

172 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4240

SKU :

4240/10

product name :

SCH 529074

description :

Restores mutant p53 activity

target :

Additional p53-related Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

563.56

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Restores mutant p53 activity. Binds p53 DNA binding domain (Kd = 1-2 M) and restores wild-type function to many oncogenic mutants by acting as a chaperone. Inhibits ubiquitination of p53 by HDM2. Triggers apoptosis in tumor cell lines and reduces tumor growth in a xenograft model.

catalog number base :

4240

product keywords :

SCH529074 p53 activates restores mutant p53 activity induces apoptosis Transcription Factors HDM2 p53 4240,

extended description :

Restores mutant p53 activity

chemical name text :

N3-[2-[[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl]methyl]-4-quinazolinyl]-N1,N1-dimethyl-1,3-propanediamine

formula :

C 31 H 36 Cl 2 N 6

formula text :

C31H36Cl2N6

cas num :

922150-11-6

2020 USD :

168

2021 USD :

172 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage