PF 04217903 mesylate | Tocris Bioscience 4239/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 04217903 mesylate

catalog :

4239/10

quantity :

10 mg

price :

353 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Leung E, Xue A, Wang Y, Rougerie P, Sharma V, Eddy R, et al. Blood vessel endothelium-directed tumor cell streaming in breast tumors requires the HGF/C-Met signaling pathway. Oncogene. 2017;36:2680-2692 pubmed publisher
Bertaux Skeirik N, Feng R, Schumacher M, Li J, Mahé M, Engevik A, et al. CD44 plays a functional role in Helicobacter pylori-induced epithelial cell proliferation. PLoS Pathog. 2015;11:e1004663 pubmed publisher
Nissen J, Selwood D, Tsirka S. Tuftsin signals through its receptor neuropilin-1 via the transforming growth factor beta pathway. J Neurochem. 2013;127:394-402 pubmed publisher

product information

brand :

Tocris

MasterCode :

4239

SKU :

4239/10

product name :

PF 04217903 mesylate

target :

MET Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

98%

observed molecular weight :

468.49

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PF 04217903 mesylate is a highly selective, high affinity MET inhibitor (Ki = 6-7 nM against wild type c-Met). Displays 1000-fold selectivity for c-Met over a panel of 208 kinases.

extended description :

Highly selective MET inhibitor

chemical name text :

4-[1-(6-Quinolinylmethyl)-1H-1,2,3-triazolo[4,5-b]pyrazin-6-yl]-1H-pyrazole-1-ethanol mesylate

formula :

C 19 H 16 N 8 O.CH 3 SO 3 H

formula text :

C19H16N8O.CH3SO3H

cas num :

956906-93-7

USD :

353 USD

product details :

Highly selective MET inhibitor

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage