TQS | Tocris Bioscience 4233 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TQS

catalog :

4233

quantity :

10 mg (also 50 mg)

price :

152 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Abbas M, Alzarea S, Papke R, Rahman S. The α7 nicotinic acetylcholine receptor positive allosteric modulator attenuates lipopolysaccharide-induced activation of hippocampal IκB and CD11b gene expression in mice. Drug Discov Ther. 2017;11:206-211 pubmed publisher

product information

brand :

Tocris

master code :

4233

SKU :

4233/10

product name :

TQS

description :

Positive allosteric modulator of 7 nAChRs

target :

Nicotinic (a7) Receptor Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

376.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Type II positive allosteric modulator of 7 nACh receptors (pEC50 = 5.5). Displays no agonist activity at 7 receptors at concentrations up to 0.1 mM; potentiates agonist-evoked responses and reduces rate of desensitization of 7 nAChRs. Exhibits potency and efficacy similar to PNU 120596 (Cat. No. 2498).

catalog number base :

4233

product keywords :

positive allosteric modulators pam alpha α a7 nicotinic receptors nachr type II Nicotinic (a7) Receptors 4233,

extended description :

Positive allosteric modulator of 7 nAChRs

chemical name text :

3a,4,5,9b-Tetrahydro-4-(1-naphthalenyl)-3H-cyclopentan[c]quinoline-8-sulfonamide

formula :

C 22 H 20 N 2 O 2 S

formula text :

C22H20N2O2S

cas num :

353483-92-8

2020 USD :

189

2021 USD :

152 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage