Dynole 34-2 | Tocris Bioscience 4222/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Dynole 34-2

catalog :

4222/10

quantity :

10 mg (also 50 mg)

price :

264 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Lukasz D, Beirl A, Kindt K. Chronic neurotransmission increases the susceptibility of lateral-line hair cells to ototoxic insults. elife. 2022;11: pubmed publisher
Lasič E, Stenovec M, Kreft M, Robinson P, Zorec R. Dynamin regulates the fusion pore of endo- and exocytotic vesicles as revealed by membrane capacitance measurements. Biochim Biophys Acta Gen Subj. 2017;1861:2293-2303 pubmed publisher
Han D, Di X, Fu Y, Mu T. Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated Î³-aminobutyric acid, type A (GABAA) receptors. J Biol Chem. 2015;290:325-37 pubmed publisher
Merezhko M, Muggalla P, Nykänen N, Yan X, Sakha P, Huttunen H. Multiplex assay for live-cell monitoring of cellular fates of amyloid-? precursor protein (APP). PLoS ONE. 2014;9:e98619 pubmed publisher

product information

brand :

Tocris

MasterCode :

4222

SKU :

4222/10

product name :

Dynole 34-2

target :

Dynamin Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

408.58

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dynole 34-2 is a dynamin I inhibitor (IC50 = 1.3 M). Inhibits receptor-mediated endocytosis (RME) (IC50 = 5.0 M).

extended description :

Dynamin I inhibitor

chemical name text :

2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide

formula :

C 25 H 36 N 4 O

formula text :

C25H36N4O

cas num :

1128165-88-7

USD :

264 USD

product details :

Dynamin I inhibitor

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage