TCS 21311 | Tocris Bioscience 4221 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS 21311

catalog :

4221

quantity :

10 mg (also 50 mg)

price :

271 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4221

SKU :

4221/10

product name :

TCS 21311

description :

Potent JAK3 inhibitor. Also inhibits GSK-3 and PKC

target :

JAK Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

526.51

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent JAK3 inhibitor (IC50 = 8 nM). Selective for JAK3 over JAK1, JAK2 and TYK2 (IC50 values are 1017, 2550 and 8055 nM respectively). Also inhibits GSK-3 , PKC and PKC (IC50 values are 3, 13 and 68 nM respectively).

catalog number base :

4221

product keywords :

TCS21311 janus kinases jaks jak3 inhibitors inhibits selective potent NIBR3049 JAK Kinase Protein Kinase C Glycogen Synthase Kinase 3 Glycogen Synthase Kinase 4221,

extended description :

Potent JAK3 inhibitor. Also inhibits GSK-3 and PKC

chemical name text :

3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

formula :

C 27 H 25 F 3 N 4 O 4

formula text :

C27H25F3N4O4

cas num :

1260181-14-3

2020 USD :

263

2021 USD :

271 USD

alt names :

NIBR3049

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage