TCS 21311 | Tocris Bioscience 4221/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

TCS 21311

catalog :

4221/10

quantity :

10 mg

price :

303 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4221

SKU :

4221/10

product name :

TCS 21311

description :

Potent JAK3 inhibitor. Also inhibits GSK-3 and PKC

target :

JAK Kinase Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

98%

storage :

Desiccate at RT

observed molecular weight :

526.51

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

TCS 21311 is a potent JAK3 inhibitor (IC50 = 8 nM). Selective for JAK3 over JAK1, JAK2 and TYK2 (IC50 values are 1017, 2550 and 8055 nM respectively). Also inhibits GSK-3 , PKC and PKC (IC50 values are 3, 13 and 68 nM respectively).

product keywords :

TCS21311 janus kinases jaks jak3 inhibitors inhibits selective potent NIBR3049 JAK Protein Kinase C Glycogen Synthase Kinase 3 Glycogen Synthase Kinase JAK Kinase 4221,

extended description :

Potent JAK3 inhibitor. Also inhibits GSK-3 and PKC

chemical name text :

3-[5-[4-(2-Hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

formula :

C27H25F3N4O4

formula text :

C27H25F3N4O4

cas num :

1260181-14-3

USD :

336

USD 2025 :

303 USD

product details :

Potent JAK3 inhibitor. Also inhibits GSK-3 and PKC

alt names :

NIBR3049