Banoxantrone dihydrochloride | Tocris Bioscience 4219 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Banoxantrone dihydrochloride

catalog :

4219

quantity :

25 mg

price :

330 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4219

SKU :

4219/25

product name :

Banoxantrone dihydrochloride

description :

Prodrug topoisomerase II inhibitor

target :

DNA Topoisomerase Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

517.4

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Bioreductive prodrug; activated by hypoxia to yield the topoisomerase II inhibitor AQ4. Displays little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 100 M). Exhibits anti-tumor efficacy in vivo when combined with oxic cell cytotoxins; enhances the anti-tumor effect of cyclophosphamide (Cat. No. 4091) in a mouse tumor model.

catalog number base :

4219

product keywords :

AQ4N prodrug hypoxia hypoxic cytotoxic topoisomerase II inhibitors inhibits antitumor antitumour chemotherapeutics AQ4N DNA Topoisomerase 4219,

extended description :

Prodrug topoisomerase II inhibitor

chemical name text :

1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride

formula :

C 22 H 28 N 4 O 6 .2HCl

formula text :

C22H28N4O6.2HCl

cas num :

252979-56-9

2020 USD :

320

2021 USD :

330 USD

alt names :

AQ4N

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage