Banoxantrone dihydrochloride | Tocris Bioscience 4219/5 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Banoxantrone dihydrochloride

catalog :

4219/5

quantity :

5 mg (also 25 mg)

price :

111 USD

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4219

SKU :

4219/5

product name :

Banoxantrone dihydrochloride

description :

Prodrug topoisomerase II inhibitor

target :

DNA Topoisomerase Inhibitors

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

517.4

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Banoxantrone dihydrochloride is a bioreductive prodrug; activated by hypoxia to yield the topoisomerase II inhibitor AQ4. Displays little to no cytotoxic activity against 60 tumor cell lines tested under oxic conditions (IC50 100 M). Exhibits anti-tumor efficacy in vivo when combined with oxic cell cytotoxins; enhances the anti-tumor effect of cyclophosphamide (Cat. No. 4091) in a mouse tumor model.

product keywords :

AQ4N prodrug hypoxia hypoxic cytotoxic topoisomerase II inhibitors inhibits antitumor antitumour chemotherapeutics AQ4N DNA Topoisomerase 4219,

extended description :

Prodrug topoisomerase II inhibitor

chemical name text :

1,4-Bis[[2-(dimethyloxidoamino)ethyl]amino]-5,8-dihydroxy-9,10-anthracenedione dihydrochloride

formula :

C22H28N4O6.2HCl

formula text :

C22H28N4O6.2HCl

cas num :

252979-56-9

USD :

109

USD 2025 :

111 USD

product details :

Prodrug topoisomerase II inhibitor

alt names :

AQ4N