4E1RCat | Tocris Bioscience 4215 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

4E1RCat

catalog :

4215

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Arnold N, Koppula P, Gul R, Lück C, Pulakat L. Regulation of cardiac expression of the diabetic marker microRNA miR-29. PLoS ONE. 2014;9:e103284 pubmed publisher

product information

brand :

Tocris

master code :

4215

SKU :

4215/10

product name :

4E1RCat

description :

Inhibits eIF4F subunit interaction; inhibits protein translation

target :

Protein-synthesizing GTPase Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

478.45

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of protein translation; blocks eIF4E:eIF4G and eIF4E:4E-BP1 interaction. Prevents assembly of the eIF4F complex and inhibits cap-dependent translation (IC50 ~4 M). Exhibits chemosensitizing properties.

catalog number base :

4215

product keywords :

eIF4F inhibitors inhibits protein synthesis chemosensitizing chemosensitizer cap dependent translation eIF4E eIF4G 4E-BP1 DNA, RNA and Protein Synthesis Protein-synthesizing GTPases 4215, Protein-synthesizing GTPase Compounds, GTP ase, EC 3.6.5.3, elongation factor, EF, initiation factor, IF, termination factor

extended description :

Inhibits eIF4F subunit interaction; inhibits protein translation

chemical name text :

4-[(3E)-3-[[5-(4-Nitrophenyl)furan-2-yl]methylidene]-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl]benzoic acid

formula :

C 28 H 18 N 2 O 6

formula text :

C28H18N2O6

cas num :

328998-25-0

2020 USD :

220

2021 USD :

225 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage