SB 297006 | Tocris Bioscience 4213/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 297006

catalog :

4213/10

quantity :

10 mg (also 50 mg)

price :

240 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

MasterCode :

4213

SKU :

4213/10

product name :

SB 297006

target :

Chemokine Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

342.35

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 297006 is a potent and selective CCR3 antagonist (IC50 = 39 nM). Displays 250-fold selectivity for CCR3 over other chemokine receptors, including CXCR1, CXCR2, CCR1 and CCR7 (IC50 27 M). Inhibits calcium mobilization induced by MCP-4, eotaxin-2 and eotaxin in RBL-2H3 cells transfected with CCR3 (IC50 values are 80, 90 and 210 nM respectively).

extended description :

Potent and selective CCR3 antagonist

chemical name text :

N-Benzoyl-4-nitroaniline ethyl ester

formula :

C 18 H 18 N 2 O 5

formula text :

C18H18N2O5

cas num :

58816-69-6

USD :

240 USD

product details :

Potent and selective CCR3 antagonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage