Ascomycin | Tocris Bioscience 4210/1 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ascomycin

catalog :

4210/1

quantity :

1 mg

price :

184 USD

product information

brand :

Tocris

master code :

4210

SKU :

4210/1

product name :

Ascomycin

target :

Protein Ser/Thr Phosphatase Inhibitors

category :

Small Molecules

unit sizes :

1 mg

observed molecular weight :

792.01

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Ascomycin is a analog of FK 506 (Cat. No. 3631); binds to FK 506-binding protein 12 (FKBP12) in order to inhibit calcineurin phosphatase activity (IC50 = 49 nM) and activation of nuclear factor of activated T cells (NFAT). Displays antifungal and immunosuppressive activities.

extended description :

Calcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631)

chemical name text :

(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-8-Ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-py

formula :

C 43 H 69 NO 12

formula text :

C43H69NO12

cas num :

104987-12-4

USD :

184 USD

product details :

Calcineurin phosphatase inhibitor; analog of FK 506 (Cat. No. 3631)

alt names :

FK 520, FR 900520

storage :

Store at -20°C