PF 3716556 | Tocris Bioscience 4191 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 3716556

catalog :

4191

quantity :

10 mg (also 50 mg)

price :

144 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4191

SKU :

4191/10

product name :

PF 3716556

description :

Selective H+,K+-ATPase inhibitor

target :

H+/K+ ATPase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

394.47

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

H+,K+-ATPase inhibitor (pIC50 = 6 in human recombinant ion-leaky assays); more potent in acidic conditions. Highly selective for H+,K+-ATPase in vitro ; displays no activity at Na+,K+-ATPase. Also displays selectivity for H+,K+-ATPase over a range of 50 receptors and ion channels (IC50 10 M). Inhibits gastric acid secretion in rat and dog models.

catalog number base :

4191

product keywords :

selective inhibitors inhibits H+K+-ATPase hydrogen potassium-ATPase ion transporters pumps ATPases PF3716556 pfizer H+,K+-ATPase 4191,

extended description :

Selective H+,K+-ATPase inhibitor

chemical name text :

8-[[(4R)-3,4-Dihydro-5-methyl-2H-1-benzopyran-4-yl]amino]-N-(2-hydroxyethyl)-N,2-dimethyl-imidazo[1,2-a]pyridine-6-carboxamide

formula :

C 22 H 26 N 4 O 3

formula text :

C22H26N4O3

cas num :

928774-43-0

2020 USD :

180

2021 USD :

144 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage