SC 26196 | Tocris Bioscience 4189 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SC 26196

catalog :

4189

quantity :

10 mg (also 50 mg)

price :

179 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Rees M, Seashore Ludlow B, Cheah J, Adams D, Price E, Gill S, et al. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nat Chem Biol. 2016;12:109-16 pubmed publisher

product information

brand :

Tocris

master code :

4189

SKU :

4189/10

product name :

SC 26196

description :

Selective fatty acid desaturase 2 inhibitor

target :

Lipid Metabolism Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

423.55

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective fatty acid desaturase 2 (FADS2, also known as 6 desaturase) inhibitor (IC50 = 0.2 M in vitro ). Displays selectivity over FADS1 and stearoly-CoA 9-desaturase ( 5 desaturase and SCD-1/ 9 desaturase, respectively) (IC50 values are 200 M in vitro ). Exhibits anti-inflammatory properties in a mouse edema model. Eliminates CSCs from ovarian cancer cell lines and inhibits sphere formation in vitro .

catalog number base :

4189

product keywords :

Pfizer SC26196 desaturases delta6 d6 6 selective inhibitors inhibits anti-inflammatory fatty acid metabolism Other Lipid Metabolism Cancer Stem Cells Other Oxygenases/Oxidases 4189,

extended description :

Selective fatty acid desaturase 2 inhibitor

chemical name text :

, -Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

formula :

C 27 H 29 N 5

formula text :

C27H29N5

cas num :

218136-59-5

2020 USD :

173

2021 USD :

179 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage