SC 26196 | Tocris Bioscience 4189/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SC 26196

catalog :

4189/10

quantity :

10 mg (also 50 mg)

price :

222 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Reichmann M, Tezera L, Vallejo A, Vukmirovic M, Xiao R, Reynolds J, et al. Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets. J Clin Invest. 2021;131: pubmed publisher
Rees M, Seashore Ludlow B, Cheah J, Adams D, Price E, Gill S, et al. Correlating chemical sensitivity and basal gene expression reveals mechanism of action. Nat Chem Biol. 2016;12:109-16 pubmed publisher

product information

brand :

Tocris

MasterCode :

4189

SKU :

4189/10

product name :

SC 26196

target :

Lipid Metabolism Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

423.55

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SC 26196 is a selective fatty acid desaturase 2 (FADS2, also known as 6 desaturase) inhibitor (IC50 = 0.2 M in vitro ). Displays selectivity over FADS1 and stearoly-CoA 9-desaturase ( 5 desaturase and SCD-1/ 9 desaturase, respectively) (IC50 values are 200 M in vitro ). Exhibits anti-inflammatory properties in a mouse edema model. Eliminates CSCs from ovarian cancer cell lines and inhibits sphere formation in vitro .

extended description :

Selective fatty acid desaturase 2 inhibitor

chemical name text :

, -Diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile

formula :

C 27 H 29 N 5

formula text :

C27H29N5

cas num :

218136-59-5

USD :

222 USD

product details :

Selective fatty acid desaturase 2 inhibitor

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage