UK 356618 | Tocris Bioscience 4187 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UK 356618

catalog :

4187

quantity :

10 mg

price :

331 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lee C, Zhan Q, Lezcano C, Frank M, Huang J, Larson A, et al. Nestin depletion induces melanoma matrix metalloproteinases and invasion. Lab Invest. 2014;94:1382-95 pubmed publisher

product information

brand :

Tocris

master code :

4187

SKU :

4187/10

product name :

UK 356618

description :

Potent and selective MMP-3 inhibitor

target :

Synthetic Metalloprotease Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

95%

observed molecular weight :

557.72

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective inhibitor of MMP-3 (IC50 = 5.9 nM). Displays selectivity over a range of MMPs (IC50 values are 73, 840, 1790, 1900 and 51000 for MMP-13, MMP-9, MMP-2, MMP-14 and MMP-1 respectively).

catalog number base :

4187

product keywords :

pfizer UK356618 matrix metalloprotease mmp selective inhibitors inhibits mmp-3 stromelysin 1 progelatinase matrix metalloproteinase Matrix Metalloprotease 4187,

extended description :

Potent and selective MMP-3 inhibitor

chemical name text :

N1-[(1S)-2,2-Dimethyl-1-[[[(1R)-1-phenylethyl]amino]carbonyl]propyl]-N4-hydroxy-2-[3-(2-methyl[1,1 -biphenyl]-4-yl)propyl]-butanediamine

formula :

C 34 H 43 N 3 O 4

formula text :

C34H43N3O4

cas num :

230961-08-7

2020 USD :

318

2021 USD :

331 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage