UK 5099 | Tocris Bioscience 4186 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

UK 5099

catalog :

4186

quantity :

10 mg (also 50 mg)

price :

184 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Tompkins S, Sheldon R, Rauckhorst A, Noterman M, Solst S, Buchanan J, et al. Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis. Cell Rep. 2019;28:2608-2619.e6 pubmed publisher
Rauckhorst A, Gray L, Sheldon R, Fu X, Pewa A, Feddersen C, et al. The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity. Mol Metab. 2017;6:1468-1479 pubmed publisher
Kaji I, Iwanaga T, Watanabe M, Guth P, Engel E, Kaunitz J, et al. SCFA transport in rat duodenum. Am J Physiol Gastrointest Liver Physiol. 2015;308:G188-97 pubmed publisher

product information

brand :

Tocris

master code :

4186

SKU :

4186/10

product name :

UK 5099

description :

MCT inhibitor; also inhibits of pyruvate transport

target :

Monocarboxylate Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

288.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC).

catalog number base :

4186

product keywords :

UK5099 inhibitor transporters mitochondrial pyruvate transport inhibitors MPT inhibits monocarboxylate transporter MCT Monocarboxylate Transporters 4186,

extended description :

MCT inhibitor; also inhibits of pyruvate transport

chemical name text :

2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid

formula :

C 18 H 12 N 2 O 2

formula text :

C18H12N2O2

cas num :

56396-35-1

2020 USD :

176

2021 USD :

184 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage