Sonepiprazole | Tocris Bioscience 4185/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Sonepiprazole

catalog :

4185/10

quantity :

10 mg (also 50 mg)

price :

192 USD

citations: 1

Reference
Nagata M, Yokooji T, Nakai T, Miura Y, Tomita T, Taogoshi T, et al. Blockade of multiple monoamines receptors reduce insulin secretion from pancreatic β-cells. Sci Rep. 2019;9:16438 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4185

SKU :

4185/10

product name :

Sonepiprazole

description :

Selective D4 antagonist

target :

Dopamine D4 Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

401.52

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Sonepiprazole is a selective, high affinity antagonist for the rat and human dopamine D4 receptor (Ki = 10 nM). Exhibits low affinity at other monoamine receptors (Ki 2000 nM). Induces c-fos gene expression in medial prefrontal cortex in a similar manner to clozapine (Cat. No. 0444). Brain penetrant and orally available.

product keywords :

Sonepiprazole selective dopamine antagonists D4 receptors dopaminergic U101387 PNU101387 pfizer PNU 101387 U 101387 D4 Receptors 4185,

extended description :

Selective D4 antagonist

chemical name text :

4-[4-[2-[(1S)-3,4-Dihydro-1H-2-benzopyran-1-yl)ethyl]-1-piperazinyl]-benzenesulfonamide

formula :

C21H27N3O3S

formula text :

C21H27N3O3S

cas num :

170858-33-0

USD :

190

USD 2025 :

192 USD

product details :

Selective D4 antagonist

alt names :

PNU 101387,U 101387