AMD 3465 hexahydrobromide | Tocris Bioscience 4179 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AMD 3465 hexahydrobromide

catalog :

4179

quantity :

10 mg (also 50 mg)

price :

214 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Luo X, Tai W, Sun L, Pan Z, Xia Z, Chung S, et al. Crosstalk between astrocytic CXCL12 and microglial CXCR4 contributes to the development of neuropathic pain. Mol Pain. 2016;12: pubmed publisher
Lourenço S, Teixeira V, Kalber T, José R, Floto R, Janes S. Macrophage migration inhibitory factor-CXCR4 is the dominant chemotactic axis in human mesenchymal stem cell recruitment to tumors. J Immunol. 2015;194:3463-74 pubmed publisher

product information

brand :

Tocris

master code :

4179

SKU :

4179/10

product name :

AMD 3465 hexahydrobromide

description :

Potent and selective CXCR4 antagonist

target :

Chemokine Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

896.07

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, selective CXCR4 antagonist; exhibits 8-fold higher affinity than AMD 3100 (Cat.No. 3299). Inhibits SDF-1 -ligand binding (Ki = 41.7 nM). Potently inhibits HIV cell entry in vitro ; causes leukocytosis and mobilizes haematopoietic stem cells in vivo .

catalog number base :

4179

product keywords :

AMD3465 CXCR4 receptor antagonist chemokine receptor chemokines antagonists Chemokine CXC Receptors 4179,

extended description :

Potent and selective CXCR4 antagonist

chemical name text :

N-[[4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)phenyl]methyl]-2-pyridinemethanamine hexahydrobromide

formula :

C 24 H 38 N 6 .6HBr

formula text :

C24H38N6.6HBr

cas num :

185991-07-5

2020 USD :

205

2021 USD :

214 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage