Pramipexole dihydrochloride | Tocris Bioscience 4174 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Pramipexole dihydrochloride

catalog :

4174

quantity :

10 mg (also 50 mg)

price :

184 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
Bonito Oliva A, Masini D, Fisone G. A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions. Front Behav Neurosci. 2014;8:290 pubmed publisher

product information

brand :

Tocris

master code :

4174

SKU :

4174/10

product name :

Pramipexole dihydrochloride

description :

Selective D3 agonist

target :

Dopamine D3 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

284.25

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Dopamine receptor agonist exhibiting selectivity for the D3 receptor (Ki values are 0.5, 3.3, 3.9 and 3.9 nM for D3, D2S, D2L and D4 receptors respectively). Exhibits negligible affinity for D1 and D5 receptors. Displays activity in the treatment of Parkinson s disease.

catalog number base :

4174

product keywords :

dopamine D3 agonists Parkinsons Disease antiparkinson parkinson s dopaminergic D3 Receptors 4174,

extended description :

Selective D3 agonist

chemical name text :

(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride

formula :

C 10 H 17 N 3 S.2HCl

formula text :

C10H17N3S.2HCl

cas num :

104632-25-9

2020 USD :

176

2021 USD :

184 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage