product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Pramipexole dihydrochloride
catalog :
4174/10
quantity :
10 mg (also 50 mg)
price :
214 USD
more info or order :
citations: 2
Reference
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed publisher
Bonito Oliva A, Masini D, Fisone G. A mouse model of non-motor symptoms in Parkinson's disease: focus on pharmacological interventions targeting affective dysfunctions. Front Behav Neurosci. 2014;8:290 pubmed publisher
product information
brand :
Tocris
master code :
4174
SKU :
4174/10
rank :
0.061
product name :
Pramipexole dihydrochloride
description :
Selective D3 agonist
target :
Dopamine D3 Receptor Agonists
category :
Small Molecules
sizes available :
10 mg (also 50 mg)
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Pramipexole dihydrochloride is a dopamine receptor agonist exhibiting selectivity for the D3 receptor (Ki values are 0.5, 3.3, 3.9 and 3.9 nM for D3, D2S, D2L and D4 receptors respectively). Exhibits negligible affinity for D1 and D5 receptors. Displays activity in the treatment of Parkinson s disease.
extended description :
Selective D3 agonist
chemical name text :
(S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride
formula :
C 10 H 17 N 3 S.2HCl
formula text :
C10H17N3S.2HCl
cas num :
104632-25-9
USD :
214 USD
product details :
Selective D3 agonist
storage :
Store the unopened product at room temperature. Do not use past expiration date.
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK