KW 3902 | Tocris Bioscience 4167 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KW 3902

catalog :

4167

quantity :

10 mg (also 50 mg)

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Cheng R, Segala E, Robertson N, Deflorian F, DorÃ© A, Errey J, et al. Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity. Structure. 2017;25:1275-1285.e4 pubmed publisher

product information

brand :

Tocris

master code :

4167

SKU :

4167/10

product name :

KW 3902

description :

Selective A1 antagonist

target :

Adenosine A1 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

356.46

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective adenosine A1 receptor antagonist; displays 890-fold selectivity for rat A1 receptors over A2A receptors (Ki values are 0.19 and 170 nM respectively). Displays no effect on recombinant rat A3 receptors expressed on CHO cells at concentrations up to 10 M. Exhibits diuretic and renal protective effects in rats.

catalog number base :

4167

product keywords :

adenosine a1 antagonists selective KW3902 Rolofylline Adenosine A1 Receptors 4167,

extended description :

Selective A1 antagonist

chemical name text :

8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione

formula :

C 20 H 28 N 4 O 2

formula text :

C20H28N4O2

cas num :

136199-02-5

2020 USD :

185

2021 USD :

191 USD

alt names :

Rolofylline

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage