KW 3902 | Tocris Bioscience 4167/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

KW 3902

catalog :

4167/10

quantity :

10 mg (also 50 mg)

price :

222 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Cheng R, Segala E, Robertson N, Deflorian F, DorÃ© A, Errey J, et al. Structures of Human A1 and A2A Adenosine Receptors with Xanthines Reveal Determinants of Selectivity. Structure. 2017;25:1275-1285.e4 pubmed publisher

product information

brand :

Tocris

master code :

4167

SKU :

4167/10

rank :

0.061

product name :

KW 3902

description :

Selective A1 antagonist

target :

Adenosine A1 Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

KW 3902 is a selective adenosine A1 receptor antagonist; displays 890-fold selectivity for rat A1 receptors over A2A receptors (Ki values are 0.19 and 170 nM respectively). Displays no effect on recombinant rat A3 receptors expressed on CHO cells at concentrations up to 10 M. Exhibits diuretic and renal protective effects in rats.

extended description :

Selective A1 antagonist

chemical name text :

8-(Hexahydro-2,5-methanopentalen-3a(1H)-yl)-3,7-dihydro-1,3-dipropyl-1H-purine-2,6-dione

formula :

C 20 H 28 N 4 O 2

formula text :

C20H28N4O2

cas num :

136199-02-5

USD :

222 USD

product details :

Selective A1 antagonist

alt names :

Rolofylline

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage