NS 5806 | Tocris Bioscience 4166 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NS 5806

catalog :

4166

quantity :

10 mg (also 50 mg)

price :

244 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gonzalez W, Pham K, Miksovska J. Modulation of the voltage-gated potassium channel (Kv4.3) and the auxiliary protein (KChIP3) interactions by the current activator NS5806. J Biol Chem. 2014;289:32201-13 pubmed publisher

product information

brand :

Tocris

master code :

4166

SKU :

4166/10

product name :

NS 5806

description :

KV4.3 channel activator

target :

Voltage-gated Potassium Channel Activators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

574.07

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

KV4.3 channel activator; mediates the transient outward K+ current (Ito). Increases IKv4.3 peak current amplitude in CHO-K1 cells expressing KV4.3 and KChIP2 (EC50 = 5.3 M). Inhibits KV1.4-mediated currents independently of KChIP2. Also slows the decay of KV4.2 and KV4.3 currents in the presence of KChIP2.

catalog number base :

4166

product keywords :

NS5806 kv4.3 channels ito transient outward potassium currents activators voltage-gated voltage-dependent K+ Voltage-Gated Potassium Channels 4166,

extended description :

KV4.3 channel activator

chemical name text :

N-[3,5-Bis(trifluoromethyl)phenyl]-N -[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea

formula :

C 16 H 8 Br 2 F 6 N 6 O

formula text :

C16H8Br2F6N6O

cas num :

426834-69-7

2020 USD :

234

2021 USD :

244 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage