product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
NS 5806
catalog :
4166/10
quantity :
10 mg (also 50 mg)
price :
307 USD
more info or order :
citations: 1
Reference
Gonzalez W, Pham K, Miksovska J. Modulation of the voltage-gated potassium channel (Kv4.3) and the auxiliary protein (KChIP3) interactions by the current activator NS5806. J Biol Chem. 2014;289:32201-13 pubmed publisher
image
image 1 :
Tocris Bioscience 4166/10 image 1
Cat.No. 4166 - NS 5806 C16H8Br2F6N6O CAS No. 426834-69-7
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
4166
SKU :
4166/10
product name :
NS 5806
description :
KV4.3 channel activator
target :
Voltage-gated Potassium Channel Activators
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
99%
storage :
Store at +4°C
observed molecular weight :
574.07
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
NS 5806 is a KV4.3 channel activator; mediates the transient outward K+ current (Ito). Increases IKv4.3 peak current amplitude in CHO-K1 cells expressing KV4.3 and KChIP2 (EC50 = 5.3 M). Inhibits KV1.4-mediated currents independently of KChIP2. Also slows the decay of KV4.2 and KV4.3 currents in the presence of KChIP2.
product keywords :
NS5806 kv4.3 channels ito transient outward potassium currents activators voltage-gated voltage-dependent K+ Voltage-Gated Potassium Channels 4166,
extended description :
KV4.3 channel activator
chemical name text :
N-[3,5-Bis(trifluoromethyl)phenyl]-N -[2,4-dibromo-6-(2H-tetrazol-5-yl)phenyl]urea
formula :
C16H8Br2F6N6O
formula text :
C16H8Br2F6N6O
cas num :
426834-69-7
USD :
303
USD 2025 :
307 USD
product details :
KV4.3 channel activator
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK