Phorbol 12,13-dibutyrate | Tocris Bioscience 4153/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Phorbol 12,13-dibutyrate

catalog :

4153/1

quantity :

1 mg

price :

89 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
van Nieuwenhuijze A, Burton O, Lemaitre P, Denton A, Cascalho A, Goodchild R, et al. Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations. Front Immunol. 2018;9:2234 pubmed publisher
Nostro M, Sarangi F, Yang C, Holland A, Elefanty A, Stanley E, et al. Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines. Stem Cell Reports. 2015;4:591-604 pubmed publisher
Sanchez A, Martinez P, Munoz M, Benedito S, Garcia Sacristan A, Hernandez M, et al. Endothelin-1 contributes to endothelial dysfunction and enhanced vasoconstriction through augmented superoxide production in penile arteries from insulin-resistant obese rats: role of ET(A) and ET(B) receptors. Br J Pharmacol. 2014;171:5682-95 pubmed publisher

product information

brand :

Tocris

master code :

4153

SKU :

4153/1

rank :

0.061

product name :

Phorbol 12,13-dibutyrate

description :

Protein kinase C activator

target :

Protein Kinase C Activators

category :

Small Molecules

sizes available :

1 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Phorbol 12,13-dibutyrate is a protein kinase C activator. Induces contraction of vascular smooth muscle and inhibits MLC phosphatase (MLCP) in vascular smooth muscle. Activity does not alter intracellular Ca2+ concentration. Also inhibits the activity of Na+,K+ ATPase in OK cells. . For more information about how Phorbol 12,13-dibutyrate may be used, see our protocol: Generation of cells from hPSCs

extended description :

Protein kinase C activator

chemical name text :

(1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-1a,1b,4,4a,5,7a,7b,8,9,9a-Decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1H-cyclopropa[3,4]benz[1,2-e]azulen-9,9a-diyl butanoic acid ester

formula :

C 28 H 40 O 8

formula text :

C28H40O8

cas num :

37558-16-0

USD :

89 USD

product details :

Protein kinase C activator

alt names :

PDBu

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage