Azidothymidine | Tocris Bioscience 4150/50 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Azidothymidine

catalog :

4150/50

quantity :

50 mg

price :

78 USD

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4150

SKU :

4150/50

product name :

Azidothymidine

Description :

Selective reverse transcriptase inhibitor; antiretroviral

target :

RNA/DNA Polymerase Inhibitors

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

267.24

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Azidothymidine is a selective reverse transcriptase inhibitor. Exhibits 100-fold selectivity for HIV reverse transcriptase over DNA polymerase . Suppresses HIV-1 replication and enhances cell viability in HIV-1 infected T cells. Attenuates growth of multiple myeloma (MM) cells in vitro and reduces growth of MM tumor xenografts in mice. Increases differentiation iPSCs into cortical neurons and reduces the over-proliferation of neural precursors. Orally bioavailable and brain penetrant. Antiretroviral agent. Also decreases CRISPR-mediated homology directed repair (HDR) efficiency.

extended description :

Selective reverse transcriptase inhibitor; antiretroviral

chemical name text :

3 -Azido-3 -deoxythymidine

formula :

C 10 H 13 N 5 O 4

formula text :

C10H13N5O4

cas num :

30516-87-1

USD :

78 USD

product details :

Selective reverse transcriptase inhibitor; antiretroviral

storage :

Store at -20°C