Pioglitazone hydrochloride | Tocris Bioscience 4124/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Pioglitazone hydrochloride

catalog :

4124/10

quantity :

10 mg (also 50 mg)

price :

89 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Merkulova A, Mitchell S, Stavrou E, Forbes G, Schmaier A. Ponatinib treatment promotes arterial thrombosis and hyperactive platelets. Blood Adv. 2019;3:2312-2316 pubmed publisher
Helmy M, Helmy M, El Mas M. Additive Renoprotection by Pioglitazone and Fenofibrate against Inflammatory, Oxidative and Apoptotic Manifestations of Cisplatin Nephrotoxicity: Modulation by PPARs. PLoS ONE. 2015;10:e0142303 pubmed publisher
Byrne F, Cheetham S, Vickers S, Chapman V. Characterisation of pain responses in the high fat diet/streptozotocin model of diabetes and the analgesic effects of antidiabetic treatments. J Diabetes Res. 2015;2015:752481 pubmed publisher
Thakran S, Zhang Q, Morales Tirado V, Steinle J. Pioglitazone restores IGFBP-3 levels through DNA PK in retinal endothelial cells cultured in hyperglycemic conditions. Invest Ophthalmol Vis Sci. 2014;56:177-84 pubmed publisher
Wahlang B, Falkner K, Clair H, Al Eryani L, Prough R, States J, et al. Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture. Toxicol Sci. 2014;140:283-97 pubmed publisher

product information

brand :

Tocris

master code :

4124

SKU :

4124/10

rank :

0.061

product name :

Pioglitazone hydrochloride

description :

Selective PPAR agonist; antidiabetic agent

target :

PPAR gamma Receptor Agonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Pioglitazone hydrochloride is a selective PPAR agonist (EC50 = 0.69 M). Thiazolidinedione (TZD) derivative and antidiabetic agent; improves insulin sensitivity. Also enhances proliferation and survival of mESCs and acts synergistically with Y-27632 (Cat. No. 1254) to improve survival of dissociated single hPSCs and increase colony formation.

extended description :

Selective PPAR agonist; antidiabetic agent

chemical name text :

5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride

formula :

C 19 H 20 N 2 O 3 S.HCl

formula text :

C19H20N2O3S.HCl

cas num :

112529-15-4

USD :

89 USD

product details :

Selective PPAR agonist; antidiabetic agent

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage