SB 772077B dihydrochloride | Tocris Bioscience 4118 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 772077B dihydrochloride

catalog :

4118

quantity :

10 mg (also 50 mg)

price :

290 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lotz Jenne C, Lüthi U, Ackerknecht S, Lehembre F, Fink T, Stritt M, et al. A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor. Oncotarget. 2016;7:25983-6002 pubmed publisher

product information

brand :

Tocris

master code :

4118

SKU :

4118/10

product name :

SB 772077B dihydrochloride

description :

Potent Rho-kinase inhibitor; vasodilator

target :

Rho-kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

415.28

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent Rho-kinase (ROCK) inhibitor (IC50 value of approximately 5.6 nM at recombinant human ROCK1 and 2). Decreases pulmonary and systemic arterial blood pressures and increases cardiac output. Exhibits vasodilator activity that is more potent than Y-27632 (Cat.No 1254) or Fasudil (Cat.No. 0541).

catalog number base :

4118

product keywords :

SB772077B 2HCl Rho Kinase inhibitors inhibits ROCK anti-inflammatory vasodilators antihypertensive Rho-kinases 4118,

extended description :

Potent Rho-kinase inhibitor; vasodilator

chemical name text :

(3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride

formula :

C 15 H 18 N 8 O 2 .2HCl

formula text :

C15H18N8O2.2HCl

cas num :

607373-46-6

2020 USD :

284

2021 USD :

290 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage