SB 772077B dihydrochloride | Tocris Bioscience 4118/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SB 772077B dihydrochloride

catalog :

4118/10

quantity :

10 mg (also 50 mg)

price :

335 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Lotz Jenne C, Lüthi U, Ackerknecht S, Lehembre F, Fink T, Stritt M, et al. A high-content EMT screen identifies multiple receptor tyrosine kinase inhibitors with activity on TGFβ receptor. Oncotarget. 2016;7:25983-6002 pubmed publisher

image

image 1 :

Cat.No. 4118 - SB 772077B dihydrochloride C15H18N8O2.2HCl CAS No. 607373-46-6

product information

brand :

Tocris

master code :

4118

SKU :

4118/10

rank :

0.061

product name :

SB 772077B dihydrochloride

description :

Potent Rho-kinase inhibitor; vasodilator

target :

Rho-kinase Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SB 772077B dihydrochloride is a potent Rho-kinase (ROCK) inhibitor (IC50 value of approximately 5.6 nM at recombinant human ROCK1 and 2). Decreases pulmonary and systemic arterial blood pressures and increases cardiac output. Exhibits vasodilator activity that is more potent than Y-27632 (Cat. No 1254) or Fasudil (Cat. No. 0541).

extended description :

Potent Rho-kinase inhibitor; vasodilator

chemical name text :

(3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride

formula :

C 15 H 18 N 8 O 2 .2HCl

formula text :

C15H18N8O2.2HCl

cas num :

607373-46-6

USD :

335 USD

product details :

Potent Rho-kinase inhibitor; vasodilator

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage