Chloroquine diphosphate | Tocris Bioscience 4109 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Chloroquine diphosphate

catalog :

4109

quantity :

50 mg

price :

54 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Tong Y, Zhang G, Li Y, Xu J, Yuan J, Zhang B, et al. Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy. J Cell Mol Med. 2018;: pubmed publisher
Gupta A, Gomes I, Wardman J, Devi L. Opioid receptor function is regulated by post-endocytic peptide processing. J Biol Chem. 2014;289:19613-26 pubmed publisher

product information

brand :

Tocris

master code :

4109

SKU :

4109/50

product name :

Chloroquine diphosphate

description :

Antimalarial; inhibits apoptosis and autophagy

target :

Antimalarials

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

515.86

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antimalarial drug. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro . Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine (Cat. No. 3977). Blocks receptor-mediated endocytosis of mannose-glycoconjugates by macrophages. Inhibits SARS-CoV-2 infection in vitro (EC50 = 1.13 M). . Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

catalog number base :

4109

product keywords :

Chloroquine diphosphate antimalarial antitumor antimetastatic autophagy apoptosis coronaviruses SARS-CoV severe acute respiratory syndrome COVID-19 endocytosis inhibitors inhibits Other Apoptosis Autophagy Antimalarials COVID-19 Endocytosis Coronavirus 4109, Malaria medication, malaria treatment

extended description :

Antimalarial; inhibits apoptosis and autophagy

chemical name text :

N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt

formula :

C 18 H 26 ClN 3 2H 3 PO 4

formula text :

C18H26ClN3?2H3PO4

cas num :

50-63-5

2020 USD :

2021 USD :

54 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage