Chloroquine diphosphate | Tocris Bioscience 4109/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Chloroquine diphosphate

catalog :

4109/50

quantity :

50 mg

price :

63 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Tong Y, Zhang G, Li Y, Xu J, Yuan J, Zhang B, et al. Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy. J Cell Mol Med. 2018;: pubmed publisher
Gupta A, Gomes I, Wardman J, Devi L. Opioid receptor function is regulated by post-endocytic peptide processing. J Biol Chem. 2014;289:19613-26 pubmed publisher

product information

brand :

Tocris

master code :

4109

SKU :

4109/50

rank :

0.061

product name :

Chloroquine diphosphate

description :

Antimalarial; inhibits apoptosis and autophagy

target :

Antimalarials

category :

Small Molecules

sizes available :

50 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Chloroquine diphosphate is an antimalarial drug. Inhibits cell growth and induces cell death in numerous cancer cell lines; inhibits cell proliferation and viability and induces apoptosis in 4T1 mouse breast cancer cells in vitro . Exhibits antimetastatic activity. Also inhibits autophagy via a mechanism distinct from that of 3-methyladenine (Cat. No. 3977). Blocks receptor-mediated endocytosis of mannose-glycoconjugates by macrophages. Inhibits SARS-CoV-2 infection in vitro (EC50 = 1.13 M). Chloroquine improves efficacy of adeno-associated viral gene transduction in vivo and in vitro , as well as enhancing non-viral gene transfection in breast cancer cells. . Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

extended description :

Antimalarial; inhibits apoptosis and autophagy

chemical name text :

N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt

formula :

C 18 H 26 ClN 3 2H 3 PO 4

formula text :

C18H26ClN3?2H3PO4

cas num :

50-63-5

USD :

63 USD

product details :

Antimalarial; inhibits apoptosis and autophagy

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage