Probenecid | Tocris Bioscience 4107/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Probenecid

catalog :

4107/50

quantity :

50 mg

price :

57 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Ostrovskaya R, Vakhitova Y, Kuzmina U, Salimgareeva M, Zainullina L, Gudasheva T, et al. Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation. J Biomed Sci. 2014;21:74 pubmed publisher
Asgari E, Le Friec G, Yamamoto H, Perucha E, Sacks S, Köhl J, et al. C3a modulates IL-1β secretion in human monocytes by regulating ATP efflux and subsequent NLRP3 inflammasome activation. Blood. 2013;122:3473-81 pubmed publisher

product information

brand :

Tocris

master code :

4107

SKU :

4107/50

rank :

0.061

product name :

Probenecid

description :

MRP and OAT3 inhibitor

target :

Multidrug Transporter Inhibitors

category :

Small Molecules

sizes available :

50 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Probenecid is an inhibitor of multidrug resistance-associated proteins (MRP). Probenicid inhibits OAT3, organic acid transport in the kidney and other organs and exhibits inhibitory activity against pannexin 1 channels (IC50 ~ 150 M). Probenecid potently inhibits SARS-CoV-2 replication in NHBE and Vero E6 cells (IC50 = 1.3 nM and 750 nM, respectively) and reduces lung virus titers in vivo . Probenicid also inhibits influenza A virus replication in vitro and in vivo .

extended description :

MRP and OAT3 inhibitor

chemical name text :

4-(Dipropylsulfamoyl)benzoic acid

formula :

C 13 H 19 NO 4 S

formula text :

C13H19NO4S

cas num :

57-66-9

USD :

57 USD

product details :

MRP and OAT3 inhibitor

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage