Amiodarone hydrochloride | Tocris Bioscience 4095/50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Amiodarone hydrochloride

catalog :

4095/50

quantity :

50 mg

price :

72 USD

citations: 2

Reference
Payne S, Ram P, Srinivasan D, Le T, Levin M, Oudin M. Potassium channel-driven bioelectric signalling regulates metastasis in triple-negative breast cancer. EBioMedicine. 2022;75:103767 pubmed publisher
Turker I, Yu C, Chang P, Chen Z, Sohma Y, Lin S, et al. Amiodarone inhibits apamin-sensitive potassium currents. PLoS ONE. 2013;8:e70450 pubmed publisher

product information

brand :

Tocris

master code :

4095

SKU :

4095/50

rank :

0.061

product name :

Amiodarone hydrochloride

description :

Broad spectrum ion channel blocker; antiarrhythmic

target :

Ion Channel Modulators

category :

Small Molecules

sizes available :

50 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Amiodarone hydrochloride is a broad-spectrum ion channel blocker; blocks late INa, ICa, IKr and IKs and increases QT. Displays class III antiarrhythmic properties. Also exhibits fungicidal activity; elicits Ca2+ influx in Saccharomyces cerevisiae and causes mitochondrial fragmentation and cell death. Thought to stimulate autophagy by targeting upstream mTORC1 control pathways. Selectively toxic to NSCs in hESC-derived cell populations. Amiodarone depolarizes the resting membrane potential of the triple-negative breast cancer (TNBC) cells and decreases cell migration.

extended description :

Broad spectrum ion channel blocker; antiarrhythmic

chemical name text :

2-Butyl-3-benzofuranyl-4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl ketone hydrochloride

formula :

C 25 H 29 I 2 NO 3 .HCl

formula text :

C25H29I2NO3.HCl

cas num :

19774-82-4

USD :

72 USD

product details :

Broad spectrum ion channel blocker; antiarrhythmic

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.