Puromycin dihydrochloride | Tocris Bioscience 4089/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Puromycin dihydrochloride

catalog :

4089/50

quantity :

50 mg

price :

101 USD

more info or order :

Tocris Bioscience product webpage

citations: 8

Reference
Yang H, Shen H, Li J, Guo L. SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance. Autophagy. 2019;:1-19 pubmed publisher
Yu X, Dobrikov M, Keir S, Gromeier M, Pastan I, Reisfeld R, et al. Synergistic antitumor effects of 9.2.27-PE38KDEL and ABT-737 in primary and metastatic brain tumors. PLoS ONE. 2019;14:e0210608 pubmed publisher
Ma S, Mao L, Deng W, Li Y, Bu L, Yu G, et al. AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinoma. Am J Transl Res. 2017;9:507-519 pubmed
Leung A, Murdoch B, Salem A, Prasad M, Gomez G, GarcÃa Castro M. WNT/Î²-catenin signaling mediates human neural crest induction via a pre-neural border intermediate. Development. 2016;143:398-410 pubmed publisher
Dasgupta S, Fishman M, Mahallati H, Castro L, Tashima A, Ferro E, et al. Reduced Levels of Proteasome Products in a Mouse Striatal Cell Model of Huntington's Disease. PLoS ONE. 2015;10:e0145333 pubmed publisher
Zhu X, Wang W, Zhang X, Bai J, Chen G, Li L, et al. All-Trans Retinoic Acid-Induced Deficiency of the Wnt/Î²-Catenin Pathway Enhances Hepatic Carcinoma Stem Cell Differentiation. PLoS ONE. 2015;10:e0143255 pubmed publisher
Dasgupta S, Castro L, Dulman R, Yang C, Schmidt M, Ferro E, et al. Proteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cells. PLoS ONE. 2014;9:e103604 pubmed publisher
Dobrikov M, Shveygert M, Brown M, Gromeier M. Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA. Mol Cell Biol. 2014;34:439-51 pubmed publisher

product information

brand :

Tocris

master code :

4089

SKU :

4089/50

rank :

0.061

product name :

Puromycin dihydrochloride

description :

Protein synthesis inhibitor

target :

DNA, RNA and Protein Synthesis Inhibitors

category :

Small Molecules

sizes available :

50 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Puromycin dihydrochloride is a protein synthesis inhibitor; leads to the premature release of polypeptide chains as polypeptidyl purine derivatives. Analog of the 3 end of aminoacyl-tRNA. Aminonucleoside antibiotic. Inhibits translation in both in vitro and in vivo systems. Also inhibits the transport of proteins into the mitochondria in vitro .

extended description :

Protein synthesis inhibitor

chemical name text :

3 -[ -Amino-p-methoxyhydrocinnamamido]-3 -deoxy-N,N-dimethyladenosine dihydrochloride

formula :

C 22 H 29 N 7 O 5 .2HCl

formula text :

C22H29N7O5.2HCl

cas num :

58-58-2

USD :

101 USD

product details :

Protein synthesis inhibitor

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage