PF 8380 | Tocris Bioscience 4078 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PF 8380

catalog :

4078

quantity :

25 mg

price :

462 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4078

SKU :

4078/25

product name :

PF 8380

description :

Potent autotaxin inhibitor

target :

Autotaxin Inhibitors

category :

Small Molecules

unit size :

25 mg

purity :

97%

observed molecular weight :

478.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent autotaxin inhibitor (IC50 = 2.8 nM in isolated enzyme assay; 101 nM in human whole blood). Modulates lysophosphatidic acid (LPA) levels in vivo and in vitro by directly inhibiting autotaxin; reduces LPA levels both in plasma and at site of inflammation. Decreases leptin-induced MMP13 expression, in vitro . Orally available.

catalog number base :

4078

product keywords :

PF8380 pfizer autotaxin lysophospholipase d inhibitors lysophosphatidic acid LPA inhibits potent Autotaxin 4078,

extended description :

Potent autotaxin inhibitor

chemical name text :

3,5-Dichlorobenzyl-[4-[3-oxo-3-(2-oxo-2,3-dihydrobenzoxazol-6-yl)propyl]]piperazine-1-carboxylate

formula :

C 22 H 21 Cl 2 N 3 O 5

formula text :

C22H21Cl2N3O5

cas num :

1144035-53-9

2020 USD :

448

2021 USD :

462 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage