SNS 032 | Tocris Bioscience 4075 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SNS 032

catalog :

4075

quantity :

10 mg (also 50 mg)

price :

254 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zhang K, Afroz S, Brownlie R, Snider M, van Drunen Littel van den Hurk S. Regulation and function of phosphorylation on VP8, the major tegument protein of bovine herpesvirus 1. J Virol. 2015;89:4598-611 pubmed publisher

product information

brand :

Tocris

master code :

4075

SKU :

4075/10

product name :

SNS 032

description :

Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

380.53

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cyclin dependent kinase (cdk) inhibitor (reported IC50 values are 0.004 - 0.048, 0.0045 - 0.05, 0.062 - 0.29, 0.2-0.48, 0.4 and 0.45 M for cdk9, cdk2, cdk7, cdk1, cdk5 and cdk4, respectively). Displays no activity against 190 additional kinases (IC50 1 M). Arrests the cell cycle at G2/M; inhibits transcription, proliferation and colony formation, and induces apoptosis in RPMI-8226 multiple myeloma cells. Prevents tumor cell-induced VEGF secretion and in vitro angiogenesis.

catalog number base :

4075

product keywords :

SNS032 inhibits cyclin-depndent kinase Cdk potent inhibitors cdk2 cdk7 cdk9 BMS387032 BMS 387032 BMS-387032 Cyclin-dependent Kinase 4075,

extended description :

Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

chemical name text :

N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide

formula :

C 17 H 24 N 4 O 2 S 2

formula text :

C17H24N4O2S2

cas num :

345627-80-7

2020 USD :

249

2021 USD :

254 USD

alt names :

BMS-387032

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage