SNS 032 | Tocris Bioscience 4075/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

SNS 032

catalog :

4075/10

quantity :

10 mg (also 50 mg)

price :

315 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Zhang K, Afroz S, Brownlie R, Snider M, van Drunen Littel van den Hurk S. Regulation and function of phosphorylation on VP8, the major tegument protein of bovine herpesvirus 1. J Virol. 2015;89:4598-611 pubmed publisher

image

image 1 :

Cat.No. 4075 - SNS 032 C17H24N4O2S2 CAS No. 345627-80-7

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4075

SKU :

4075/10

product name :

SNS 032

Description :

Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

target :

Cyclin-dependent Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

380.53

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

SNS 032 is a cyclin dependent kinase (cdk) inhibitor (reported IC50 values are 0.004 - 0.048, 0.0045 - 0.05, 0.062 - 0.29, 0.2-0.48, 0.4 and 0.45 M for cdk9, cdk2, cdk7, cdk1, cdk5 and cdk4, respectively). Displays no activity against 190 additional kinases (IC50 1 M). Arrests the cell cycle at G2/M; inhibits transcription, proliferation and colony formation, and induces apoptosis in RPMI-8226 multiple myeloma cells. Prevents tumor cell-induced VEGF secretion and in vitro angiogenesis.

extended description :

Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

chemical name text :

N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide

formula :

C 17 H 24 N 4 O 2 S 2

formula text :

C17H24N4O2S2

cas num :

345627-80-7

USD :

315 USD

product details :

Cdk inhibitor; potently inhibits cdk2, cdk7 and cdk9

alt names :

BMS-387032

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage