6-Thioguanine | Tocris Bioscience 4061 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

6-Thioguanine

catalog :

4061

quantity :

50 mg

price :

47 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

4061

SKU :

4061/50

product name :

6-Thioguanine

description :

Anticancer and immunosuppressive agent

target :

Immunosuppressants

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

167.19

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Anticancer and immunosuppressive agent often used to treat immune disorders and leukemia. Displays cytotoxic and antineoplastic properties; disrupts cytosine methylation by DNA methyltransferases after incorporation into DNA. Selectively kills BRCA2-defective tumors in a xenograft model. Also facilitates proteasome-mediated degradation of DNA (cytosine-5)-methyltransferase 1 (DNMT1). Also inhibits SARS-CoV papain-like protease (PLpro; IC50 = 5 M for PLpro deubiquitination activity).

catalog number base :

4061

product keywords :

6-TG anticancer chemotherapeutics immunosupprressive agents cytotoxic antineoplastic cancer BRCA2 tumors epigenetics antimetabolites 6-TG DNA Methyltransferases Immunosuppressants Papain-like Proteases 4061,

extended description :

Anticancer and immunosuppressive agent

chemical name text :

2-Amino-6-mercaptopurine

formula :

C 5 H 5 N 5 S

formula text :

C5H5N5S

cas num :

154-42-7

2020 USD :

2021 USD :

47 USD

alt names :

6-TG

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage