L-Ascorbic acid | Tocris Bioscience 4055 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-Ascorbic acid

catalog :

4055

quantity :

50 mg

price :

49 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed publisher
Shahraz A, Kopatz J, Mathy R, Kappler J, Winter D, Kapoor S, et al. Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages. Sci Rep. 2015;5:16800 pubmed publisher
Guindon J, Deng L, Fan B, Wager Miller J, Hohmann A. Optimization of a cisplatin model of chemotherapy-induced peripheral neuropathy in mice: use of vitamin C and sodium bicarbonate pretreatments to reduce nephrotoxicity and improve animal health status. Mol Pain. 2014;10:56 pubmed publisher
Lu J, Liu H, Huang C, Chen H, Du Z, Liu Y, et al. Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep. 2013;3:1580-91 pubmed publisher
Yeligar S, Tsukamoto H, Kalra V. Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothelial cells involves hypoxia-inducible factor-1alpha and microrNA-199. J Immunol. 2009;183:5232-43 pubmed publisher

product information

brand :

Tocris

master code :

4055

SKU :

4055/50

product name :

L-Ascorbic acid

description :

Enhances the generation of iPSCs; increases reprogramming efficiency

target :

Compounds for Induced Pluripotent Stem Cells

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

176.12

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of Cav3.2 channels (IC50 = 6.5 M); displays no effect on Cav3.1 or Cav3.3 channels heterologously expressed in HEK 293 cells. Also enhances the generation of induced pluripotent stem cells (iPSCs) from mouse and human somatic cells by increasing reprogramming efficiency. Commonly used antifade reagent in live cell microscopy. Naturally occurring antioxidant.

catalog number base :

4055

product keywords :

L-Ascorbic acid Vc vitamin C ascorbate calcium channels t-type CaV3.2 selective Ca2+ channel blockers voltage-gated voltage-dependent iPSC stem cells antifade reagents live cell imaging blinking photobleaching. L-Ascorbate Vitamin C Cav3.x Channels Stem Cell Reprogramming Antioxidants Antifade Reagents 4055, Stem cells cellular dedifferentiation totipotent pluripotent multipotent oligopotent unipotent embryonic ESC specialization specialisation specialized specialised

extended description :

Enhances the generation of iPSCs; increases reprogramming efficiency

chemical name text :

3-Oxo-L-gulofuranolactone

formula :

C 6 H 8 O 6

formula text :

C6H8O6

cas num :

50-81-7

2020 USD :

2021 USD :

49 USD

alt names :

L-Ascorbate, Vitamin C

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage