L-Ascorbic acid | Tocris Bioscience 4055/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-Ascorbic acid

catalog :

4055/50

quantity :

50 mg

price :

58 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Tristan C, Ormanoglu P, Slamecka J, Malley C, Chu P, Jovanovic V, et al. Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells. Stem Cell Reports. 2021;16:3076-3092 pubmed publisher
Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed publisher
Shahraz A, Kopatz J, Mathy R, Kappler J, Winter D, Kapoor S, et al. Anti-inflammatory activity of low molecular weight polysialic acid on human macrophages. Sci Rep. 2015;5:16800 pubmed publisher
Guindon J, Deng L, Fan B, Wager Miller J, Hohmann A. Optimization of a cisplatin model of chemotherapy-induced peripheral neuropathy in mice: use of vitamin C and sodium bicarbonate pretreatments to reduce nephrotoxicity and improve animal health status. Mol Pain. 2014;10:56 pubmed publisher
Lu J, Liu H, Huang C, Chen H, Du Z, Liu Y, et al. Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Cell Rep. 2013;3:1580-91 pubmed publisher
Yeligar S, Tsukamoto H, Kalra V. Ethanol-induced expression of ET-1 and ET-BR in liver sinusoidal endothelial cells and human endothelial cells involves hypoxia-inducible factor-1alpha and microrNA-199. J Immunol. 2009;183:5232-43 pubmed publisher

product information

brand :

Tocris

master code :

4055

SKU :

4055/50

rank :

0.061

product name :

L-Ascorbic acid

description :

Enhances the generation of iPSCs; increases reprogramming efficiency

target :

Compounds for Induced Pluripotent Stem Cells

category :

Small Molecules

sizes available :

50 mg

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

L -Ascorbic acid is an inhibitor of Cav3.2 channels (IC50 = 6.5 M); displays no effect on Cav3.1 or Cav3.3 channels heterologously expressed in HEK 293 cells. Also enhances the generation of induced pluripotent stem cells (iPSCs) from mouse and human somatic cells by increasing reprogramming efficiency. Commonly used antifade reagent in live cell microscopy. Naturally occurring antioxidant. . For more information about how L-Ascorbic acid may be used, see our protocol: Highly Efficient Generation of CiPSCs from MEFs

extended description :

Enhances the generation of iPSCs; increases reprogramming efficiency

chemical name text :

3-Oxo-L-gulofuranolactone

formula :

C 6 H 8 O 6

formula text :

C6H8O6

cas num :

50-81-7

USD :

58 USD

product details :

Enhances the generation of iPSCs; increases reprogramming efficiency

alt names :

L-Ascorbate, Vitamin C

storage :

Store the unopened product at room temperature. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage