PT 1 | Tocris Bioscience 4039 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PT 1

catalog :

4039

quantity :

25 mg

price :

342 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Asiedu M, Han C, Dib Hajj S, Waxman S, Price T, Dussor G. The AMPK Activator A769662 Blocks Voltage-Gated Sodium Channels: Discovery of a Novel Pharmacophore with Potential Utility for Analgesic Development. PLoS ONE. 2017;12:e0169882 pubmed publisher
Huang L, Dai K, Chen M, Zhou W, Wang X, Chen J, et al. The AMPK Agonist PT1 and mTOR Inhibitor 3HOI-BA-01 Protect Cardiomyocytes After Ischemia Through Induction of Autophagy. J Cardiovasc Pharmacol Ther. 2016;21:70-81 pubmed publisher

product information

brand :

Tocris

master code :

4039

SKU :

4039/25

product name :

PT 1

description :

AMPK activator

target :

AMPK Activators

category :

Small Molecules

unit size :

25 mg

purity :

98%

observed molecular weight :

497.91

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer ( 1 1 1) activity (EC50 = 0.3 M). Selectively increases the activity of 1- but not 3-containing complexes. Thought to directly activate AMPK by antagonizing autoinhibition.

catalog number base :

4039

product keywords :

AMPK amp-activated protein kinase activators PT1 AMPK Enzyme Substrates/ Activators 4039,

extended description :

AMPK activator

chemical name text :

2-Chloro-5-[[5-[[5-(4,5-Dimethyl-2-nitrophenyl)-2-furanyl]methylene]-4,5-dihydro-4-oxo-2-thiazolyl]amino]benzoic acid

formula :

C 23 H 16 ClN 3 O 6 S

formula text :

C23H16ClN3O6S

cas num :

331002-70-1

2020 USD :

332

2021 USD :

342 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage