BRD 7389 | Tocris Bioscience 4037/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BRD 7389

catalog :

4037/10

quantity :

10 mg (also 50 mg)

price :

240 USD

citations: 3

Reference
Park Y, Remmers E, Lee W, Ombrello A, Chung L, Shilei Z, et al. Ancient familial Mediterranean fever mutations in human pyrin and resistance to Yersinia pestis. Nat Immunol. 2020;21:857-867 pubmed publisher
Gwinn D, Lee A, Briones Martin del Campo M, Conn C, Simpson D, Scott A, et al. Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase. Cancer Cell. 2018;33:91-107.e6 pubmed publisher
Breindel J, Haskins J, Cowell E, Zhao M, Nguyen D, Stern D. EGF receptor activates MET through MAPK to enhance non-small cell lung carcinoma invasion and brain metastasis. Cancer Res. 2013;73:5053-65 pubmed publisher

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

4037

SKU :

4037/10

product name :

BRD 7389

Description :

Ribosomal S6 kinase inhibitor

target :

RSK Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

97%

observed molecular weight :

366.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

BRD 7389 is a ribosomal S6 kinase (RSK) inhibitor (IC50 values are 1.2, 1.5 and 2.4 M for RSK3, RSK1 and RSK2 respectively). Upregulates insulin expression in terminally differentiated pancreatic -cells.

extended description :

Ribosomal S6 kinase inhibitor

chemical name text :

1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione

formula :

C 24 H 18 N 2 O 2

formula text :

C24H18N2O2

cas num :

376382-11-5

USD :

240 USD

product details :

Ribosomal S6 kinase inhibitor

storage :

Store at -20°C