5'-Fluoroindirubinoxime | Tocris Bioscience 4033/10 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

5'-Fluoroindirubinoxime

catalog :

4033/10

quantity :

10 mg (also 50 mg)

price :

134 USD

product information

brand :

Tocris

master code :

4033

SKU :

4033/10

product name :

5'-Fluoroindirubinoxime

description :

FLT3 inhibitor; displays antiproliferative activity

target :

Flt-3 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

295.27

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

5 -Fluoroindirubinoxime is an inhibitor of FMS-like receptor tyrosine kinase-3 (FLT3) (IC50 = 15 nM). Displays selectivity for FLT3 against 6 other kinases including EGFR. Displays antiproliferative activity against the MV4;11 cell line (expressing constitutively active FLT3) and a number of cancer cell lines, including SNU-638 (stomach carcinoma) and HT-1080 (fibrosarcoma).

catalog number base :

4033

extended description :

FLT3 inhibitor; displays antiproliferative activity

chemical name text :

5 -Fluoro-1H,1 H-[2,3 ]biindolylidene-3,2 dione 3-oxime

formula :

C 16 H 10 FN 3 O 2

formula text :

C16H10FN3O2

cas num :

861214-33-7

USD 2021 :

134

USD 2022 :

134 USD

product details :

FLT3 inhibitor; displays antiproliferative activity

storage :

Store at +4°C