JNJ 7777120 | Tocris Bioscience 4021/5 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JNJ 7777120

catalog :

4021/5

quantity :

5 mg (also 25 mg)

price :

109 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Hayes M, Ward S, Crawford G, Seoane R, Jackson W, Kipling D, et al. Inflammation-induced IgE promotes epithelial hyperplasia and tumour growth. elife. 2020;9: pubmed publisher
Meixiong J, Anderson M, Limjunyawong N, Sabbagh M, Hu E, Mack M, et al. Activation of Mast-Cell-Expressed Mas-Related G-Protein-Coupled Receptors Drives Non-histaminergic Itch. Immunity. 2019;50:1163-1171.e5 pubmed publisher
Glatzer F, Gschwandtner M, Ehling S, Rossbach K, Janik K, Klos A, et al. Histamine induces proliferation in keratinocytes from patients with atopic dermatitis through the histamine 4 receptor. J Allergy Clin Immunol. 2013;132:1358-67 pubmed publisher

image

image 1 :

Cat.No. 4021 - JNJ 7777120 C14H16ClN3O CAS No. 459168-41-3

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

4021

SKU :

4021/5

product name :

JNJ 7777120

description :

Selective H4 antagonist

target :

Histamine H4 Receptor Antagonists

unit size :

5 mg (also 25 mg)

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

277.75

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JNJ 7777120 is a histamine H4 receptor antagonist; displays high affinity (Ki = 4.5 nM) and is 1000-fold selective for H4 over other histamine receptors.

product keywords :

JNJ7777120 histamine 4 histaminergic H4 receptors antagonists selective Histamine H4 Receptors 4021,

extended description :

Selective H4 antagonist

chemical name text :

1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine

formula :

C14H16ClN3O

formula text :

C14H16ClN3O

cas num :

459168-41-3

USD :

121

USD 2025 :

109 USD

product details :

Selective H4 antagonist

more info or order :

Tocris Bioscience product webpage