IDE 2 | Tocris Bioscience 4016 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IDE 2

catalog :

4016

quantity :

10 mg (also 50 mg)

price :

191 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Borowiak M, Maehr R, Chen S, Chen A, Tang W, Fox J, et al. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell. 2009;4:348-58 pubmed publisher

product information

brand :

Tocris

master code :

4016

SKU :

4016/10

product name :

IDE 2

description :

Induces definitive endoderm formation in mouse and human ESCs

target :

Compounds for Stem Cell Differentiation

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

240.3

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cell-permeable inducer of definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 223 nM for induction of Sox17 expression in ESCs). Reported to activate TGF- signaling and downstream Smad2 phosphorylation; upregulates Nodal expression. Promotes pancreatic progenitor cell formation in vitro , and gut tube formation in vivo .

catalog number base :

4016

product keywords :

IDE2 inducer induces endodermal formation embryonic stem cells differentiation ESCs nodal sox17 ESCs and iPSC 4016, differentiation stem cells, DIFFERENTIATION STEM CELLS

extended description :

Induces definitive endoderm formation in mouse and human ESCs

chemical name text :

Heptanedioic acid-1-(2-cyclopentylidenehydrazide)

formula :

C 12 H 20 N 2 O 3

formula text :

C12H20N2O3

cas num :

1136466-93-7

2020 USD :

185

2021 USD :

191 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage