IDE 1 | Tocris Bioscience 4015 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IDE 1

catalog :

4015

quantity :

10 mg (also 50 mg)

price :

244 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Xu F, Liu J, Deng J, Chen X, Wang Y, Xu P, et al. Rapid and high-efficiency generation of mature functional hepatocyte-like cells from adipose-derived stem cells by a three-step protocol. Stem Cell Res Ther. 2015;6:193 pubmed publisher
Kearns N, Genga R, Ziller M, Kapinas K, Peters H, Brehm M, et al. Generation of organized anterior foregut epithelia from pluripotent stem cells using small molecules. Stem Cell Res. 2013;11:1003-12 pubmed publisher
Borowiak M, Maehr R, Chen S, Chen A, Tang W, Fox J, et al. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell. 2009;4:348-58 pubmed publisher

product information

brand :

Tocris

master code :

4015

SKU :

4015/10

product name :

IDE 1

description :

Induces definitive endoderm formation in mouse and human ESCs

target :

Compounds for Stem Cell Differentiation

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

306.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Induces definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 125 nM). Thought to activate the TGF- signaling pathway; induces Smad2 phosphorylation and increases levels of Nodal expression. . This compound is mixture of E/Z isomers.

catalog number base :

4015

product keywords :

IDE1 stem cells induces definitive endoderm human mouse ESCs tgfb transforming growth factors beta b signaling signalling nodal ESCs and iPSC 4015, differentiation stem cells, DIFFERENTIATION STEM CELLS

extended description :

Induces definitive endoderm formation in mouse and human ESCs

chemical name text :

1-[2-[(2-Carboxyphenyl)methylene]hydrazide]heptanoic acid

formula :

C 15 H 18 N 2 O 5

formula text :

C15H18N2O5

cas num :

1160927-48-9

2020 USD :

234

2021 USD :

244 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage