IDE 1 | Tocris Bioscience 4015/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

IDE 1

catalog :

4015/10

quantity :

10 mg (also 50 mg)

price :

283 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Xu F, Liu J, Deng J, Chen X, Wang Y, Xu P, et al. Rapid and high-efficiency generation of mature functional hepatocyte-like cells from adipose-derived stem cells by a three-step protocol. Stem Cell Res Ther. 2015;6:193 pubmed publisher
Kearns N, Genga R, Ziller M, Kapinas K, Peters H, Brehm M, et al. Generation of organized anterior foregut epithelia from pluripotent stem cells using small molecules. Stem Cell Res. 2013;11:1003-12 pubmed publisher
Borowiak M, Maehr R, Chen S, Chen A, Tang W, Fox J, et al. Small molecules efficiently direct endodermal differentiation of mouse and human embryonic stem cells. Cell Stem Cell. 2009;4:348-58 pubmed publisher

product information

brand :

Tocris

master code :

4015

SKU :

4015/10

rank :

0.071

product name :

IDE 1

description :

Induces definitive endoderm formation in mouse and human ESCs

target :

Compounds for Stem Cell Differentiation

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

IDE 1 is an induces definitive endoderm formation in mouse and human embryonic stem cells (ESCs) (EC50 = 125 nM). Thought to activate the TGF- signaling pathway; induces Smad2 phosphorylation and increases levels of Nodal expression. . This compound is mixture of E/Z isomers.

extended description :

Induces definitive endoderm formation in mouse and human ESCs

chemical name text :

1-[2-[(2-Carboxyphenyl)methylene]hydrazide]heptanoic acid

formula :

C 15 H 18 N 2 O 5

formula text :

C15H18N2O5

cas num :

1160927-48-9

USD :

283 USD

product details :

Induces definitive endoderm formation in mouse and human ESCs

storage :

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage