product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
MK 217
catalog :
4014/50
quantity :
50 mg
price :
101 USD
more info or order :
Tocris Bioscience product webpage
product information
brand :
Tocris
SKU :
4014/50
product name :
MK 217
unit sizes :
50 mg
description :
Inhibitor of farnesyl diphosphate synthase (FPPS) and osteoclast-mediated bone resorption
target :
Synthase/Synthetase Inhibitors
category :
Small Molecules
observed molecular weight :
271.08
details of functionality :
Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts.
catalog number base :
4014
extended description :
Inhibitor of farnesyl diphosphate synthase (FPPS) and osteoclast-mediated bone resorption
chemical name text :
P,P -(4-Amino-1-hydroxybutylidene)bis-phosphonic acid monosodium salt
formula :
C 4 H 12 NNaO 7 P 2
formula text :
C4H12NNaO7P2
cas num :
129318-43-0
USD :
101 USD
product details :
Inhibitor of farnesyl diphosphate synthase (FPPS) and osteoclast-mediated bone resorption
alt names :
Alendronate sodium
storage :
Desiccate at -20°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK