L 760735 | Tocris Bioscience 4013/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L 760735

catalog :

4013/10

quantity :

10 mg (also 50 mg)

price :

306 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Yin J, Chapman K, Clark L, Shao Z, Borek D, Xu Q, et al. Crystal structure of the human NK1 tachykinin receptor. Proc Natl Acad Sci U S A. 2018;115:13264-13269 pubmed publisher

image

image 1 :

Cat.No. 4013 - L 760735 C26H28F7N5O2.HCl CAS No. 188923-01-5

product information

brand :

Tocris

master code :

4013

SKU :

4013/10

rank :

0.061

product name :

L 760735

description :

High affinity NK1 antagonist

target :

NK1 Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

L 760735 is a high affinity NK1 receptor antagonist (IC50 = 0.19 nM at human NK1 receptors). Selective ( 300-fold) over h-NK2 and h-NK3 receptors. Exhibits anxiolytic and antidepressant-like effects. Orally active.

extended description :

High affinity NK1 antagonist

chemical name text :

5-[[(2R,3S)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]methyl-N,N-dimethyl-1H-1,2,3-triazole-4-methanamine hydrochloride

formula :

C 26 H 28 F 7 N 5 O 2 .HCl

formula text :

C26H28F7N5O2.HCl

cas num :

188923-01-5

USD :

306 USD

product details :

High affinity NK1 antagonist

storage :

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

Tocris Bioscience product webpage